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In Vitro Reconstitution of Dynein Force Exertion in a Bulk Viscous Medium

Abstract : Highlights d A bulk motility assay reconstitutes dynein pulling microtubules in the cytoplasm d A single motile cargo in a viscous solution generates near pN forces on a microtubule d Forces are additive, recapitulating a length-dependent model d Tug-of-war situations yield centration of minimal asters in bulk
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https://hal.archives-ouvertes.fr/hal-03025707
Contributor : Benjamin Lacroix <>
Submitted on : Thursday, November 26, 2020 - 3:53:40 PM
Last modification on : Monday, December 28, 2020 - 10:56:05 AM

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Héliciane Palenzuela, Benjamin Lacroix, Jérémy Sallé, Katsuhiko Minami, Tomohiro Shima, et al.. In Vitro Reconstitution of Dynein Force Exertion in a Bulk Viscous Medium. Current Biology - CB, Elsevier, 2020, 30 (22), pp.4534-4540.e7. ⟨10.1016/j.cub.2020.08.078⟩. ⟨hal-03025707⟩

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